Mike Byrne is a founding partner of Anomaly and Global Creative Chief, where he helped lead Anomaly to Agency of the Year in 2022, Ad Age A-list #1 in 2017 as well as seven top ten placements seven years in a row. He helped lead Anomaly to two-time Fast Company Most innovative Companies on top of other industry accolades.

He spent his formative years in advertising at Wieden & Kennedy NY then Portland where he served as the co-creative chief for the agency's cornerstone Nike Account from 2000 – 2006. During his tenure, W+K Portland amassed more awards than any other agency in the United States. W+K Portland was Agency of the Year two times in this tenure. While at W+K, Mike managed creative development for Nike in the US, Latin America and Europe.